Mint Neurotechnologies, Amber Therapeutics, and Imperial College London announce the GOLD project: a strategic partnership to develop advanced chip technology for neural implants.

May 31, 2024

Mint Neurotechnologies Ltd (MintNeuro) is excited to announce the start of an £800k collaboration, supported by Innovate UK under the Smart grant scheme for the project "Reconfigurable semiconductor technology for advanced neural implants” (short name: “GOLD”). The project is led by Dr. Dorian Haci, CEO at MintNeuro, and brings together a strategic partnership between MintNeuro, Amber Therapeutics Ltd (Amber), and Imperial College London.

Neurological conditions are the leading cause of disability and the second cause of death worldwide. Monitoring and treating these conditions is incredibly challenging due to protective layers like the skull and membranes, which shield the brain, spine, and nerves. These critical areas are difficult to access, complicating the delivery of effective interventions.

Advanced neural implants, which include electronics placed inside the body close to the nervous system, represent a breakthrough technology. They have the potential to revolutionise our understanding and treatment of the brain, enabling people to walk again, allowing children to hear for the first time, and alleviating symptoms of epilepsy, Parkinson's disease, and other debilitating conditions.

“We are pioneering the use of semiconductor technology to build a platform that will pave the way for countless future innovations and therapies.”

– Dr. Dorian Haci, MintNeuro

However, current implants are highly invasive and can take years and hundreds of millions of pounds to develop, posing a significant barrier and risk for innovators, investors, and small and medium-sized companies. An important factor is the need for complex electronics that must meet strict constraints for size and power, while also adhering to stringent regulatory requirements for Active Implantable Medical Devices.

The GOLD project aims to create a set of modular, medical-grade chips that address these challenges. Advanced packaging techniques will combine these chips into tiny systems to enable medical device companies and researchers to rapidly address different needs. This approach minimises implant size and power consumption, opening up new surgical procedures and techniques that reduce patient risk. Moreover, by leveraging the economies of scale inherent in the semiconductor industry, this innovation is set to make neural implants more cost-effective and accessible.

This partnership will co-develop a "neural chipset"—a group of function specific chips designed to work together in multiple applications—and integrate it into a single device. This will first form the electronics of an implantable medical device for treating mixed urinary incontinence, a severe debilitating condition with no singular treatment option currently. Ultimately, it will enable the creation of new device therapies for other medical conditions that can be addressed through the nervous system. 

Dr. Dorian Haci, CEO of MintNeuro, commented: "We are at the cusp of a new era in medical technology, where the power of modular design can lead to unprecedented advancements in bioelectronic interventions for neurological conditions. Our collaboration is not just about creating a new implantable device. We are pioneering the use of semiconductor technology to build a platform that will pave the way for countless future innovations and therapies. Together with our partners, we are committed to bridging the gap between advanced medical research and real-world applications."

Dr. Sean Doherty, Amber’s Director of R&D, added: "We are thrilled to be partnering with the experts at MintNeuro and Imperial on the GOLD project. Developing novel therapies in the active implantable medical device space requires significant time and investment, often development of custom chipsets is beyond scope for early-stage companies. The development of a modular neural chipset designed to combine high-level performance with miniaturised footprints has the potential to bring huge benefits to innovation in this space."

Prof. Timothy Constandinou, Professor of Bioelectronics at Imperial, said: "The GOLD project is exciting and completes the translational journey. I look forward to working closely with our spinout MintNeuro, and partner Amber to bring our chipset architecture for neural implants to market, and most importantly, to the clinic."

About Mint Neurotechnologies

MintNeuro is an innovative startup at the dynamic intersection of neurotechnology and semiconductors. The team is pioneering integrated circuit solutions for implantable medical devices targeting the management and treatment of neurological conditions. MintNeuro aims to deliver scalable, less invasive, and highly efficient devices that transform neurological care.

About Amber Therapeutics

Amber Therapeutics is developing next-generation, intelligent bioelectrical therapies to transform clinical outcomes in patients with functional disorders of the peripheral nervous system. Amber's approach leverages closed-loop intelligence to create 'synthetic reflex arcs' that can sense, interpret, adapt and respond to a patient's individual signals thereby restoring normal physiological function.

About Imperial College London

Imperial College London is a world-leading university with the mission to achieve enduring excellence in research and education in science, engineering, medicine and business (STEMB) for the benefit of society.

About Innovate UK

Innovate UK, part of UK Research and Innovation (UKRI), is creating a better future by inspiring, involving and investing in businesses developing life-changing innovations. Innovate UK provides targeted sectors with expertise, facilities and funding to test, demonstrate and evolve their ideas, driving UK productivity and economic growth.


For more information, please contact:

Dorian Haci ( dorian@mintneuro.com )

Mint Neurotechnologies Ltd, 125 Wood Street, London, EC2V 7AW, United Kingdom

Tim Denison ( tim@amber-tx.com ) 

Amber Therapeutics Ltd, Cannon Place, 78 Cannon Street, London, EC4N 6AF, United Kingdom

Timothy Constandinou ( t.constandinou@imperial.ac.uk ) 

Imperial College London, South Kensington Campus, London, SW7 2AZ, United Kingdom

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